Pathophysiology of depression

1) Describe the pathophysiology of depression.
2) Discuss the phenomenon of depression’s effects on appetite. Describe from a pathophysiologic basis why some people with depression experience a lack of appetite resulting in weight loss while others will experience increased food intake and have weight gain.
3)Discuss two additional clinical findings of depression and present the pathophysiologic basis of these symptoms.
B)
1)Explain the action of thyroid hormone. (Your answer should contain the impact of the thyroid hormone on functions in the body).
2) Discuss the negative feedback loop of thyroid function.
3) Select either hypothyroidism or hyperthyroidism and define the clinic presentation providing the pathophysiologic process underlying the clinical presentation.

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